Spider-Man 2

From The Film Guide

Spider-Man 2 is the second film in the Spider-Man series of films directed by Sam Raimi. It stars Tobey Macguire as the masked hero, and also stars Kirsten Dunst, Alfred Molina, James Franco, and Rosemary Harris. This time, the stress of being Spider-Man, attending college, and working two jobs as a delivery boy and a photographer for the Daily Bugle begins to eat at Peter, and after his powers decide to "glitch", he decides he is Spider-Man no more. In a sick turn of events, Peter's idol, Doctor Otto Octavius's lab experiment, funded by OsCorp., goes haywire, and turns him into the evil Doc Ock. Now, Peter must stop him before he destroys the city, or worse, even the world.